منابع مشابه
A Microfluidic, High Throughput Protein Crystal Growth Method for Microgravity
The attenuation of sedimentation and convection in microgravity can sometimes decrease irregularities formed during macromolecular crystal growth. Current terrestrial protein crystal growth (PCG) capabilities are very different than those used during the Shuttle era and that are currently on the International Space Station (ISS). The focus of this experiment was to demonstrate the use of a comm...
متن کاملHigh-Quality Protein Crystal Growth of Mouse Lipocalin-Type Prostaglandin D Synthase in Microgravity
Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) catalyzes the isomerization of PGH(2) to PGD(2) and is involved in the regulation of pain and of nonrapid eye movement sleep and the differentiation of male genital organs and adipocytes, etc. L-PGDS is secreted into various body fluids and binds various lipophilic compounds with high affinities, acting also as an extracellular transporter. ...
متن کاملNumerical model of protein crystal growth in a diffusive field such as the microgravity environment
It is said that the microgravity environment positively affects the quality of protein crystal growth. The formation of a protein depletion zone and an impurity depletion zone due to the suppression of convection flow were thought to be the major reasons. In microgravity, the incorporation of molecules into a crystal largely depends on diffusive transport, so the incorporated molecules will be ...
متن کاملNonconstant Tip Velocity in Microgravity Dendritic Growth
Pivalic acid dendrites grown and observed as part of the USMP-4 isothermal dendritic growth experiment aboard the space shuttle Columbia show an initial transient followed by an accelerating tip growth that may approach a constant growth rate. The mechanism responsible for this behavior is not as yet clear and may be due to experimental factors such as the long-range thermal interactions betwee...
متن کاملEffect of Spaceship Orbital Transfer on Solution Convection during Protein Crystal Growth under Microgravity
Detailed numerical analysis is presented for the effect of spaceship orbital transfer on solution convection during protein crystal growth under microgravity. The results show that the flow and mass transfer during protein crystal growth are unsteady in the process of orbital transfer. For the case of quasi-steady acceleration, the flow is so weak that the effect of flow on concentration field ...
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ژورنال
عنوان ژورنال: Journal of the Mineralogical Society of Japan
سال: 1992
ISSN: 1883-7018,0454-1146
DOI: 10.2465/gkk1952.21.263